Direct detection and identification of active pharmaceutical ingredients in intact tablets by helium plasma ionization (HePI) mass spectrometry
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چکیده
منابع مشابه
Direct detection and identification of active pharmaceutical ingredients in intact tablets by helium plasma ionization (HePI) mass spectrometry
A simple modification converts an electrospray ion source to an ambient-pressure helium plasma ionization source without the need of additional expensive hardware. Peaks for active ingredients were observed in the spectra recorded from intact pharmaceutical tablets placed in this source. A flow of heated nitrogen was used to thermally desorb analytes to gas phase. The desorption temperatures we...
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ژورنال
عنوان ژورنال: Journal of Pharmaceutical Analysis
سال: 2014
ISSN: 2095-1779
DOI: 10.1016/j.jpha.2013.09.010